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In the discovery cycle, for the predictions of the effects that a drug will display, measurement of its specific functional response induced in a biological system ‘a bioassay’ is required. The bioassay is thus an essential tool for research and development. Bioassays based on the in vitro responses of enzymes or stable cell lines are commonly the assay systems of choice for this purpose. These bio-assays are rapid, reproducible, economical, sample hungry. |