Analytical laboratory work in state-of-the-art facilities with cutting edge equipment and analytical infrastructure to cater to the demands of Food and Pharmaceutical Industry. This Laboratory offers the analytical services required to meet Pharmacopeial and Food Chemical Codex (FCC) monograph standards. Natural Remedies uses established and standard methodologies as the Association of Analytical Chemists (AOAC), Pharmacopoeial, BIS etc,. In cases where existing methodologies are not sufficient, Natural Remedies has the expertise and resources to develop and validate assays.

Stability studies / Shelf life:

Stability studies / Shelf life: Shelf-life refers to the period from initial preparation to packaging during which the drug dosage form continues to remain within its physical, chemical, therapeutic and toxicological specifications at specified storage conditions.The stability of the product is its ability to resist deterioration. It is always expressed in terms of shelf life. Natural Remedies offers stability management services for Active Neutraceutical Ingredients (APIs) and finished products. The facilities are equipped with temperature and humidity-controlled chambers that are continuously monitored and alarmed for any environmental changes. All the chambers undergo stringent IQ, OQ, PQ and calibration processes on a yearly basis and are fully mapped (empty and full) for both temperature and humidity to ensure temperature/humidity uniformity. The chambers meet complete ICH conditions, including 25°C/60% RH, 30°C/65% RH, 40°C/75%RH, 5°C.

  • Real Time Stability Studies and Testing
  • Accelerated Aging Stability Studies and Testing
  • Stress testing

Analytical Services List

# Botanical Name Marker(s) / active compounds
1 Acorus calamus a-asarone
2 Adhatoda vasica Vasicine
3 Aegle marmelos Marmelosin
4 Albizia lebbeck (+)-Catechin
5 Aloe vera Aloin
6 Andrographis paniculata Andrographolide
7 Anethum sowa Anethol
8 Asparagus racemosus Shatavarin-I and Shatavarin-IV
9 Bacopa monnieri Bacoside-A
10 Berberis aristata Berberine
11 Boerhaavia diffusa Eupalitin& Eupalitin-3-O-galactoside
12 Boswellia serrata Acetyl keto boswellic acid, Keto Boswellic acid
13 Capsicum annum Capsaicin
14 Cassia angustifolia Sennosides
15 Cassia tora Chrysophanol
16 Coleus forskohlii Forskolin
17 Commiphora mukul Guggulsterone-E & Z
18 Curcuma longa Curcumin
19 Eclipta alba Wedelolactone
20 Gardenia gummifera Gardenin
21 Gloriosa superba Colchicine
22 Glycyrrhiza glabra Glycyrrhizin
23 Gymnema sylvestre Gymnemagenin
24 Largerstroemia speciosa Corosolic acid
25 Mallotus philippensis Rottlerin
26 Mangifera indica Mangiferin
27 Mangifera indica Mangiferin
28 Mucuna pruriens L-Dopa
29 Ocimum tenuiflorum Rosemarinic acid, Ursolic acid
30 Peganum harmala Harmaline, Harmine
31 Phyllanthus amarus Phyllanthin, Hypophyllanthin
32 Piper longum / Piper nigrum Piperine
33 Plumbago zeylanica Plumbagin
34 Psoralea corylifolia Psoralen
35 Terminalia arjuna Arjungenin, Arjunic acid
36 Tribulus terrestris Tribulosin
37 Trigonella-foenum-graecum Trigonelline
38 Valeriania officinalis Valerenic acid
39 Vitex negundo Agnuside
40 Withania somnifera Withanolide-A & B, Withastramonolide, Withanoside- IV & V, Withaferin-A
41 Zingiber officinale 6-gingerol, 6-Shogaol, 8-gingerol
# Botanical Name Marker(s) / active compounds
1 Acacia catechu Catechins
2 Adhatoda vasica Vasicine
3 Aegle marmelos Marmelosin
4 Aesculus indica b-escin
5 Andrographis paniculata Andrographolide
6 Aristolochia indica Aristolochic acid
7 Bacopa monnieri Bacoside A, Bacopaside I, Bacosine
8 Bacopa monnieri Bacoside-A
9 Berberis aristata Berberine
10 Boswellia serrata Boswellic acids
12 Camellia sinensis EGCG (Epigalocatechin gallate) and Total Catechins
13 Cassia angustifolia Sennosides A & B
14 Cassia tora Chrysophanol
15 Capsicum annum Capsaicin
16 Centella asiatica Asiaticoside and Madecassoside
17 Coleus forskohlii Forskolin
18 Chrysanthemum parthenium Parthenolide
19 Curcuma longa Curcumin
20 Eclipta alba Wedelolactone & demethylwedelolactone
21 Embelia ribes Embelin
22 Ferula asafoetida Ferulic acid
23 Garcinia cambogia Hydroxy citric acid
24 Garcinia mangostana Mangostin
25 Gardenia gummifera Gardenin
26 Gloriosa superba Colchicine
27 Glycyrrhiza glabra Glabridin
28 Glycyrrhiza glabra Glycyrrhizin
29 Gymnema sylvestre Gymnemagenin
30 Hypericum perforatum Hypericin
31 Lagerstroemia speciosa Corosolic acid
32 Mallotus philippensis Rottlerin
33 Mangifera indica Mangiferin
34 Mucuna pruriens L-Dopa
35 Ocimum tenuiflorum Rosemarinic acid & Ursolic acid
36 Peganum harmala Harmine & Harmaline
37 Phyllanthus amarus Phyllanthin and Hypophyllanthin
38 Plumbago zeylanica Plumbagin
39 Crataeva nurvala Lupeol
40 Hedychium spicatum Para methoxy ethyl cinnamate
41 Ocimum Tenuiflorum Ursolic and Oleanolic acid
42 Valeriania officinalis Valerenic acid
43 Asparagus racemosus Shatavarin-I and Shatavarin-IV
44 Trigonella graceum 4-Hydroyisoleucine
# #
1 Solubility 27 Acid Value
2 Ash 28 Saponification value
3 Acid Insoluble ash 29 Peroxide value
4 pH 30 Free fatty acids
5 Bulk Density 31 Hydroxyl value
6 Aristolochia indica 32 Ester value
7 Tapped Bulk Density 33 Acetyl value
8 Total Soluble Solids 34 Unsapamisiable value
9 Average Weight 35 Iodine Value
10 Uniformity of Weight 36 Friability test
11 Average Fill 37 Total Foreign matter
12 Variation from Average Fill 38 Total Dissolved Solids
13 Disintegration Test 39 Ether Soluble Extractive(Fixed Oil)
14 Hardness Test 40 Crude Fibre
15 Specific Gravity 41 Protein / Nitrogen Estimation
16 Weight / ml 42 Pressure Test in Aerosols
17 Acidity 43 Leakage Test in Aerosols
18 Loss on Drying at 105°C 44 Peroxide value
19 Spreadability 45 Sedimentation Test in Aerosols
20 Clarity of Solution 46 Optical Rotation
21 Consistency 47 Specific Optical Rotation
22 Melting Range 48 Determination of Cineole
23 Boiling Range 49 Loss on ignition
24 Congealing Temperature 50 Sulphated ash
25 Refractive index 51 Particle Size
26 Viscosity By Brookfield
# Solvent Analysis by GC Head Space
1 Methanol
2 Ethanol
3 Acetone
4 Hexane
5 Ethylacetate
7 n-butanol
8 Toluene
9 Tetrahydrofuran
10 Dichloromethane
# Polycyclic Aromatic Hydrocarbons (PAHs)
1 benz[a]anthracene
2 benzo[a]pyrene
# Heavy metal analysis
1 Lead
2 Mercury
3 Arsenic
4 Cadmium
# Mycotoxins
1 Aflatoxins (B1 + B2 + G1 + G2)
2 Ochrotoxins (A & B)
# Naturally Occuring Toxins Test
1 Aristolocholic acid
2 Hypericin
3 Harmal alkaloids
4 Coumarin
5 Methyl eugenol
# Other metals
1 Zinc
2 Copper
3 Aluminium
4 Chromium
5 Cobalt
6 Copper
7 Iron
8 Manganese
9 Barium
10 Tin
11 Nickle
12 Beryllium
13 Vanadium
14 Molybdenum
A wide variety of diseases and dermatological problems are caused by infectious agents. Bacteria plays an important role in the etiology of variety of infectious diseases. Discovery of novel and potent antimicrobial substances help in the management of infectious conditions.

Minimum Inhibitory Concentration (MIC):

The MIC test determines antimicrobial activity of a material against a specific bacteria. The lowest concentration of the test agent that allows no growth/ no more than one or two CFU/ only a slight haze to grow is the MIC. The minimal bactericidal concentration (MBC) or the minimum lethal concentration (MLC) is defined as the lowest concentration of the test agent that will kill a test organism, MLC cannot be done without testing for MIC.

Zone of Inhibition:

This method is used to demonstrate activity / potency of antimicrobials or antibiotics /plant materials by measuring the zone of inhibition against specified microorganisms. This method is very useful for screening of large number of test agents for their antimicrobial activities. The test agents showing good antimicrobial activity can then be taken for MIC studies.

Bioburden Testing:

Bioburden testing will provide an estimate of the total number of bacteria, fungus, etc. present in your sample. Bioburden testing on the products and other ingredients used in the pharmaceutical /food/nutraceutical industry provide control of microbial levels. Bioburden testing determines the number of viable microorganisms on a product.

Environmental Monitoring (Surface testing, equipment testing, air monitoring, glove print)*

The Environmental (Microbial) monitoring programs for controlled environments should assess the effectiveness of the cleaning and sanitation practices by and of the personnel that could have an impact on the bioburden of the controlled environment. Microbial monitoring, regardless of how sophisticated the system may be, will not and need not identify and quantitative all microbial contaminants present in controlled environments. Routine microbiological monitoring should provide sufficient information to ascertain that the controlled environment is operating within an adequate state of control.

The Environmental monitoring program includes an appropriate level of identification of the flora obtained from sampling. A knowledge of the normal flora in controlled environments aids in determining the usual microbial flora anticipated for the facility being monitored, evaluating the effectiveness of the cleaning and sanitation procedures, methods and agents and recovery methods.

Water analysis*

Bacteriological water analysis is a method of analyzing water to estimate the numbers of bacteria present and, if needed, to find out what sort of bacteria they are. It is a microbiological analytical procedure which uses samples of water and from these samples determines the concentration of bacteria. It is then possible to draw inferences about the suitability of the water for use from these concentrations. This process is used, for example, to routinely confirm that water is safe for human consumption or that bathing and recreational waters are safe to use.

The interpretation and the action trigger levels for different waters vary depending on the use made of the water. Very stringent levels applying to drinking water whilst more relaxed levels apply to marine bathing waters where much lower volumes of water are expected to be ingested by users.

  • Total Aerobic count
  • Yeast & Mould Count (TFC)
  • Enterobacteriaceae
  • Coliforms
  • E.coli
  • Salmonella
  • Stapylococcus aureus
  • Pseudomonas aeruginosa

Note: *Services available within Bangalore

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