Randomized double- blind placebo controlled clinical study of KalmCold® with 223 adults suffering from two or more symptoms of common cold and gave treatment for 5 days.
This graph shows the overall symptoms score wherein KalmCold® showed significant reduction compared to placebo.
Effect of KalmCold® on inflammatory mediators
Based on pre-clinical studies, the effect of KalmCold® was studied on LPS induced immune cells which reduced the levels of inflammatory mediators like NO, PGE 2 , IL-1 beta and IL-6 in J774A.
|INFLAMMATORY MEDIATORS||LINKED TO|
|LTB4||Bronchoconstriction, inflammation and mucus secretion|
|PGE2, TXB2||Bronchoconstriction and inflammation|
|Cytokines (IL-6, IL-1β)||Bronchoconstriction, inflammation, mucus secretion & sore throat|
|Nitric oxide||Bronchoconstriction, inflammation and cell migration|