Supports Stress Management Naturally

OciBest® is a clinically tested standardized herbal composition derived from Ocimum tenuiflorum to support stress management. It is phytochemically standardized to ociglycoside-I (>0.1% w/w), rosmarinic acid (>0.2% w/w) and triterpene acids (>2.5% w/w).

WHAT IS OCIBEST ®

Ocimum tenuiflorum (Tulasi) is considered as an adaptogen- balancing different processes in the body and helpful for adapting to stress symptoms like forgetfulness, sexual problems of recent origin, frequent feeling of exhaustion and sleep problems.

Ocimum has been clinically tested to manage all the symptoms of stress.

CLINICAL STUDY

Randomized double-blind placebo controlled clinical study with OciBest® on volunteers suffering from at least three symptoms of stress

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OciBest® reduced the stress symptoms by 1.6 times than placebo.

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PRE- CLINICAL STUDY

OciBest® was tested in the chronic variable model of stress(CVS). CVS involved the use of 6 different types of stressors with 2 stressors per day on 30 Albino Wistar Rats. Stressors applied on all days during the experimental period except on days of evaluation.

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OciBest® improves the ability to cope with stress.

MODES OF ACTION

OciBest® helps cope with everyday stress possibly by acting against CRHR1 receptor,
inhibiting cortisol release, 11β-HSD1 and COMT

Cortisol is a stress hormone. Sustained presence of cortisol in plasma is an indication of chronic stress and is detrimental to health. CRHR1 is receptor seen in pituitary gland. CRH binds to this receptor and is responsible for cortisol release. OciBest® acts against the CRHR1 receptor.

1

11β-HSD1 is involved in the activation of cortisol. OciBest® acts against it.

2

OciBest® inhibits COMT which plays a central role in the metabolic inactivation of catecholic neurotransmitters, such as dopamine, norepinephrine, and epinephrine. Catecholic neurotransmitters help manage stress.

3

HEALTH BENEFITS AND DOSE

Supports stress management naturally.

Helps manage following stress symptoms

Forgetfulness

Frequent feeling of exhaustion

Frequent sleep problems

Dose

1200 mg/day

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