Whitepaper

KOLIN PLUS® - Proof of Concept Studies

Comprehensive Scientific Evidence Demonstrating Efficacy, Stability, and Regulatory Compliance

Choline is an essential nutrient in poultry nutrition, playing a critical role in lipid metabolism, hepatic function, cell membrane integrity, and overall growth and productivity. Although synthetic choline chloride (SCC) has traditionally been used to meet dietary choline requirements, its high hygroscopicity, negative impact on feed stability, oxidative degradation of fat-soluble vitamins, and adverse interactions with trace minerals and enzymes limit it’s effectiveness; moreover, SCC is not permitted in organic production systems. With increasing regulatory scrutiny and rising demand for clean label, sustainable feed solutions, the poultry industry is shifting toward natural, phytogenic alternatives that can effectively replace SCC while supporting lipid metabolism, preventing fatty liver, enhancing hepatic antioxidant status, improving nutrient utilization and performance, ensuring stability in feed and premix systems, and complying with organic and natural feed regulations.Kolin Plus®, a proprietary polyherbal formulation developed by Natural Remedies Pvt. Ltd., combines Acacia nilotica and Curcuma longa. Kolin Plus® has been found to be an effective replacement for synthetic choline chloride. This white paper provides an in-depth scientific evaluation of Kolin Plus®, spanning preclinical, zootechnical, biochemical, and genomic evidence to prove its suitability as a natural alternative to synthetic choline chloride.

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KOLIN PLUS® - Proof of Concept Studies

“Preclinical, Zootechnical, Biochemical, and Genomic Evidence Supporting Efficacy and Safety”

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